Losartan + Hydrochlorothiazide (Hyzaar)
$1.32
Hyzaar combines Losartan with a water tablet to control high blood pressure when a single medicine is not enough.
Drug Information
5 reviews for Losartan + Hydrochlorothiazide (Hyzaar)
Hyzaar combines two blood pressure medicines in one tablet: losartan and hydrochlorothiazide. It is used when one medicine alone has not lowered blood pressure enough.
What is it used for?
- High blood pressure (hypertension)
- Lowering stroke risk in people with high blood pressure and a thickened heart
How does it work?
Losartan relaxes and widens blood vessels by blocking the hormone angiotensin II. Hydrochlorothiazide is a "water tablet" that helps the kidneys remove extra salt and water. Together they lower blood pressure more than either one alone.
This information is written in simple words to help you understand this product. It does not replace advice from your doctor or pharmacist.
Read these points before you start. If any of them apply to you, talk to your doctor or pharmacist first.
- High blood pressure usually has no symptoms, so keep taking your medicine even when you feel well. Stopping can make your blood pressure rise again.
- It can make you feel dizzy, especially when you stand up quickly or when you first start. Get up slowly from sitting or lying down.
- Alcohol can make dizziness worse and raise blood pressure over time. Keep it to small amounts.
- Tell your doctor if you have kidney or liver problems.
- Have your blood pressure checked regularly, as your doctor advises.
- Do not take it if you are pregnant or trying to become pregnant. It can harm the unborn baby. Tell your doctor straight away if you become pregnant.
- Do not use potassium supplements or salt substitutes that contain potassium unless your doctor says so.
- Painkillers like ibuprofen and naproxen can reduce its effect and affect your kidneys. Ask your pharmacist before taking them.
- Tell your doctor if you take lithium, or aliskiren (especially if you have diabetes).
- If you have diarrhoea or sickness and cannot keep fluids down, ask your doctor whether to pause it for a day or two.
- The water tablet can raise blood sugar and uric acid (tell your doctor if you have diabetes or gout), lower potassium and salt levels, and make skin more sensitive to sunlight.
- Do not take it if you are allergic to "sulfa" medicines or pass very little urine.
- Tell your doctor or pharmacist about every other medicine, vitamin or herbal product you use.
- Keep this product out of the reach and sight of children.
Like all medicines, Hyzaar can cause side effects, but not everybody gets them.
Common side effects
- Dizziness
- Feeling tired
- Headache
- Back or muscle pain
- Needing to pass urine more often
These are usually mild and often get better as your body gets used to it. Tell your doctor if they bother you or do not go away.
Stop using it and get medical help straight away if you notice:
- Fainting, or feeling like you are going to faint
- Swelling of the face, lips, tongue or throat, or trouble breathing or swallowing
- Muscle weakness, a slow or uneven heartbeat (possible high potassium)
- Passing much less urine than usual
- Sudden eye pain or blurred vision
- Severe thirst, muscle cramps, confusion or weakness
This is not a complete list. If you notice anything unusual, ask your doctor or pharmacist.
- Take one tablet once a day, preferably in the morning so you are not up at night to pass urine.
- Swallow it with a glass of water. You can take it with or without food.
- It can take 2 to 4 weeks to see the full effect.
If you miss a dose: Take it as soon as you remember the same day. If it is nearly time for your next dose, skip the missed one. Never take two doses at once.
If you use too much: Contact your doctor, a poison control centre or your local emergency number straight away, even if you feel fine. Take the pack with you.
How to store it: Keep it in its original pack at room temperature (below 25°C / 77°F), away from heat, damp and direct sunlight. Do not use it after the expiry date.
- QDo I need to take Hyzaar for the rest of my life?
- A
Often, yes. High blood pressure is usually a long-term condition. Your doctor will review your treatment over time. Do not stop without talking to them.
- QCan I drink alcohol with Hyzaar?
- A
Small amounts are usually fine, but alcohol can make you dizzy and can raise your blood pressure. Try to keep within safe limits.
- QWhat else can help my blood pressure?
- A
Eating less salt, staying active, keeping a healthy weight, not smoking and cutting down on alcohol all help your medicine work better.
- QWill Hyzaar give me a cough?
- A
A dry cough is uncommon with this type of medicine. It is often used for people who got a cough from ACE inhibitors like lisinopril.

Diya Richardson –
Found what I needed on this site without any trouble. I received everything in good time. No surprise fees at checkout, which I appreciated.
Ishaan Flores –
A friend told me about this site, so I gave it a go. The outer box was discreet and the inside was well arranged. The wait for delivery was short and painless.
Amina Mensah –
I was a little nervous about ordering Hyzaar online, but it turned out fine. It arrived sealed and in good shape. Nothing negative to say, it was a good one.
Rafael Carter –
I had no issues with what I received. The team kept me updated on the status of my Hyzaar order. Browsing the site was pleasant and the search worked well. Thank you, I will be ordering again.
Ali Petit –
I used this site for my latest order and had no problems. The price for Hyzaar was reasonable and there were no hidden charges. And the expiry date was fine and everything looked as it should.