Jakura 5mg medication is primarily used to treat autoimmune diseases. The 5 mg dosage is commonly prescribed for treating conditions like rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and ankylosing spondylitis. Sometimes, it is used off-label for conditions like alopecia areata or ankylosing spondylitis. The medicine helps decrease pain and swelling in joints by reducing inflammation and tenderness; it slows down the progression of bone and joint damage. Jakura can be prescribed as a single medicine or in combination with other medicines, depending on a patient’s health. Working of the drug Tofacitinib is the main active ingredient present in Jakura 5mg. It belongs to a class of drugs called Janus kinase (JAK) inhibitors. JAK enzymes play a role in the signaling pathways involved in the immune system, specifically in the production of inflammatory cytokines that contribute to the pathology of autoimmune diseases. By inhibiting JAK1, JAK2, JAK3, and sometimes TYK2 (depending on the formulation), tofacitinib reduces the inflammatory response and helps control symptoms of autoimmune conditions.

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