Sulfasalazine (Azulfidine)
$0.72
Azulfidine (Sulfasalazine) treats ulcerative colitis and rheumatoid arthritis by reducing inflammation in the bowel and joints.
Drug Information
4 reviews for Sulfasalazine (Azulfidine)
Azulfidine contains Sulfasalazine.
Sulfasalazine is a medicine for ulcerative colitis, Crohn's disease affecting the colon, and rheumatoid arthritis. It reduces inflammation in the bowel and in joints.
What is it used for?
- Ulcerative colitis and colonic Crohn's disease
- Rheumatoid arthritis
- Some other types of inflammatory arthritis
How does it work?
In the bowel, sulfasalazine is split into two parts: mesalamine, which calms bowel inflammation, and sulfapyridine, which helps calm joint inflammation.
This information is written in simple words to help you understand this product. It does not replace advice from your doctor or pharmacist.
Read these points before you start. If any of them apply to you, talk to your doctor or pharmacist first.
- Do not take it if you are allergic to "sulfa" medicines or aspirin.
- You will need regular blood tests, especially in the first 3 months, to check your blood count and liver.
- Tell your doctor if you have liver or kidney problems, G6PD deficiency or porphyria.
- It can lower sperm count in men while taking it. This returns to normal after stopping.
- It can turn urine, sweat and tears orange-yellow and stain soft contact lenses.
- Tell your doctor or pharmacist about every other medicine, vitamin or herbal product you use.
- Keep this product out of the reach and sight of children.
Like all medicines, Azulfidine can cause side effects, but not everybody gets them.
Common side effects
- Feeling sick, loss of appetite
- Headache
- Rash
- Orange-yellow urine (harmless)
These are usually mild and often get better as your body gets used to it. Tell your doctor if they bother you or do not go away.
Stop using it and get medical help straight away if you notice:
- Sore throat, fever, mouth ulcers or unusual bruising (possible blood problems)
- Yellowing of the skin or eyes
- A severe rash with blisters or peeling
This is not a complete list. If you notice anything unusual, ask your doctor or pharmacist.
- Take it with food and a glass of water, spacing doses evenly.
- Swallow the enteric-coated tablets whole.
- Your doctor will start low and increase slowly. A common dose for arthritis is 2 g a day in divided doses. For bowel disease, 1 g to 2 g four times a day during a flare.
- Drink plenty of fluids.
If you miss a dose: Take it as soon as you remember, unless it is nearly time for your next dose. Never take two doses at once.
If you use too much: Contact your doctor, a poison control centre or your local emergency number straight away, even if you feel fine. Take the pack with you.
How to store it: Keep it in its original pack at room temperature (below 25°C / 77°F), away from heat, damp and direct sunlight. Do not use it after the expiry date.
- QWhy is my urine orange on Azulfidine?
- A
This is a harmless effect of the medicine.
- QHow long does Azulfidine take to help arthritis?
- A
Usually 6 to 12 weeks.
- QCan I wear contact lenses with Azulfidine?
- A
Soft contact lenses may be stained yellow. You may prefer glasses.

Petra Cruz –
Ordered Sulfasalazine a few days ago and wanted to leave a quick review. Payment went through smoothly on the first try. Reasonably priced and the discount at checkout was a nice touch. Solid experience, nothing to complain about.
Khalid Boateng –
Placed an order for Azulfidine and it was handled well. Their staff was patient with my questions. Navigation is simple, even for someone who is not great with websites. On top of that, tracking worked well and the delivery went exactly as planned.
Sophie Singh –
I used this site for my latest order and had no problems. I had a question about my Azulfidine order and the support team replied fast. Would happily recommend it.
Caleb Yang –
My experience with this order was good. Service was courteous from start to finish. Adding it to the cart and paying was quick.