Nortriptyline (Pamelor)
$0.52
Pamelor contains Nortriptyline and treats depression, and is also used for nerve pain and migraine prevention.
Drug Information
5 reviews for Nortriptyline (Pamelor)
Pamelor contains Nortriptyline.
Nortriptyline is a tricyclic antidepressant. It treats depression and, in lower doses, nerve pain. It tends to cause fewer side effects than some other medicines of its kind.
What is it used for?
- Depression
- Nerve pain
- Preventing migraine (off-label)
- Helping people stop smoking (off-label)
How does it work?
Nortriptyline raises the level of noradrenaline (and some serotonin) in the brain and spinal cord, which improves mood and calms pain signals.
This information is written in simple words to help you understand this product. It does not replace advice from your doctor or pharmacist.
Read these points before you start. If any of them apply to you, talk to your doctor or pharmacist first.
- Antidepressants can, rarely, cause thoughts of self-harm or suicide, especially in people under 25 and in the first few weeks. Tell someone close to you that you are taking it and ask them to tell you if they notice changes in your mood or behaviour.
- Do not take it with, or within 2 weeks of, an MAOI antidepressant (such as phenelzine or selegiline), or with linezolid or methylene blue.
- Taking it with other medicines that raise serotonin (other antidepressants, tramadol, triptans for migraine, lithium, St John's wort) can cause serotonin syndrome.
- It can raise the risk of bleeding, especially with aspirin, ibuprofen, naproxen or blood thinners.
- Tell your doctor if you have epilepsy, bipolar disorder or mania, glaucoma, heart problems, liver or kidney problems, or diabetes.
- Do not stop taking it suddenly. This can cause withdrawal symptoms like dizziness, electric-shock feelings, bad dreams and irritability. Your doctor will lower the dose slowly.
- It may make you sleepy or dizzy. Do not drive until you know how it affects you, and avoid alcohol.
- Tell your doctor if you are pregnant, planning a pregnancy or breastfeeding.
- Do not take it if you have recently had a heart attack or have heart rhythm problems. Tell your doctor about any heart disease.
- Tell your doctor if you have glaucoma, trouble passing urine, an enlarged prostate, constipation, an overactive thyroid or porphyria.
- An overdose can be very dangerous. Keep it out of the reach of children and others at risk.
- Tell your doctor or pharmacist about every other medicine, vitamin or herbal product you use.
- Keep this product out of the reach and sight of children.
Like all medicines, Pamelor can cause side effects, but not everybody gets them.
Common side effects
- Feeling sick (nausea), especially in the first 1 to 2 weeks
- Headache
- Trouble sleeping or feeling sleepy
- Sweating
- Dry mouth
- Lower sex drive, or trouble reaching orgasm or getting an erection
- Constipation
- Blurred vision
- Dizziness when standing up
- Weight gain
These are usually mild and often get better as your body gets used to it. Tell your doctor if they bother you or do not go away.
Stop using it and get medical help straight away if you notice:
- Thoughts of harming yourself or ending your life
- Feeling very high, overexcited or reckless (mania)
- Fever, sweating, shaking, muscle twitching, fast heartbeat and confusion (possible serotonin syndrome)
- A fit (seizure)
- Unusual bleeding or bruising, or black stools
- Confusion, headache and weakness, especially in older people (low sodium)
- A fast, pounding or uneven heartbeat, or fainting
- Being unable to pass urine
- Eye pain with blurred vision and red eye
This is not a complete list. If you notice anything unusual, ask your doctor or pharmacist.
- Take it once a day at bedtime, or in divided doses, as your doctor tells you.
- A common adult dose for depression is 25 mg three or four times a day, or 75 mg to 100 mg at bedtime. Lower doses are used for pain.
- Swallow the capsule with water. You can take it with or without food.
If you miss a dose: Take it as soon as you remember, unless it is nearly time for your next dose. Never take two doses at once.
If you use too much: Contact your doctor, a poison control centre or your local emergency number straight away, even if you feel fine. Take the pack with you.
How to store it: Keep it in its original pack at room temperature (below 25°C / 77°F), away from heat, damp and direct sunlight. Do not use it after the expiry date.
- QHow long does Pamelor take to work?
- A
Some people notice better sleep or energy in 1 to 2 weeks, but it usually takes 4 to 6 weeks to feel the full benefit on mood. Keep taking it even if you do not feel different straight away.
- QHow long will I need to take Pamelor?
- A
Most people take it for at least 6 months after they feel better, to stop the depression or anxiety coming back. Your doctor will review this with you.
- QCan I drink alcohol with Pamelor?
- A
It is best to avoid alcohol. It can make you more drowsy and can make depression and anxiety worse.
- QIs Pamelor addictive?
- A
No, antidepressants are not addictive. But stopping suddenly can cause withdrawal-like symptoms, so always reduce slowly with your doctor.

Bilal Hassan –
Placed an order for Nortriptyline and it was handled well. The parcel reached me without any delays. I should add that the total I saw at checkout was the total I paid. Besides that, everything was packed carefully and nothing was damaged. All good on my side!
Ishaan Ahmed –
I was a little nervous about ordering Nortriptyline online, but it turned out fine. The layout makes it easy to find what you are after. The parcel arrived a day or two sooner than I figured.
Layla Ramos –
I ordered Pamelor from here last week and the whole thing was hassle free. I checked everything against my order and it was all correct. Also, the delivery took about as long as I was told. It was a pleasant experience and I am glad I chose this site.
Lei Baker –
Got it faster than I was expecting, which was nice. For the price, I could not ask for more. Easy to order Pamelor here, and I will do it again.
Zainab Gutierrez –
I ordered from here after comparing a few options. The item looked exactly like the listing. Everything went well, so I will be back.