Clomipramine (Anafranil)
$0.32
Anafranil (Clomipramine) treats obsessive compulsive disorder, depression and panic attacks by balancing chemicals in the brain.
Drug Information
16 reviews for Clomipramine (Anafranil)
Anafranil contains Clomipramine.
Clomipramine is a tricyclic antidepressant. It is especially useful for obsessive compulsive disorder (OCD), and is also used for depression, panic attacks and some phobias.
What is it used for?
- Obsessive compulsive disorder (OCD)
- Depression
- Panic disorder and phobias
- Cataplexy linked to narcolepsy
How does it work?
Clomipramine strongly increases serotonin levels in the brain, which helps reduce obsessive thoughts and compulsive urges, and improves mood.
This information is written in simple words to help you understand this product. It does not replace advice from your doctor or pharmacist.
Read these points before you start. If any of them apply to you, talk to your doctor or pharmacist first.
- Antidepressants can, rarely, cause thoughts of self-harm or suicide, especially in people under 25 and in the first few weeks. Tell someone close to you that you are taking it and ask them to tell you if they notice changes in your mood or behaviour.
- Do not take it with, or within 2 weeks of, an MAOI antidepressant (such as phenelzine or selegiline), or with linezolid or methylene blue.
- Taking it with other medicines that raise serotonin (other antidepressants, tramadol, triptans for migraine, lithium, St John's wort) can cause serotonin syndrome.
- It can raise the risk of bleeding, especially with aspirin, ibuprofen, naproxen or blood thinners.
- Tell your doctor if you have epilepsy, bipolar disorder or mania, glaucoma, heart problems, liver or kidney problems, or diabetes.
- Do not stop taking it suddenly. This can cause withdrawal symptoms like dizziness, electric-shock feelings, bad dreams and irritability. Your doctor will lower the dose slowly.
- It may make you sleepy or dizzy. Do not drive until you know how it affects you, and avoid alcohol.
- Tell your doctor if you are pregnant, planning a pregnancy or breastfeeding.
- Do not take it if you have recently had a heart attack or have heart rhythm problems. Tell your doctor about any heart disease.
- Tell your doctor if you have glaucoma, trouble passing urine, an enlarged prostate, constipation, an overactive thyroid or porphyria.
- An overdose can be very dangerous. Keep it out of the reach of children and others at risk.
- Tell your doctor if you have epilepsy. Clomipramine can make seizures more likely, especially at high doses.
- Tell your doctor or pharmacist about every other medicine, vitamin or herbal product you use.
- Keep this product out of the reach and sight of children.
Like all medicines, Anafranil can cause side effects, but not everybody gets them.
Common side effects
- Feeling sick (nausea), especially in the first 1 to 2 weeks
- Headache
- Trouble sleeping or feeling sleepy
- Sweating
- Dry mouth
- Lower sex drive, or trouble reaching orgasm or getting an erection
- Constipation
- Blurred vision
- Dizziness when standing up
- Weight gain
These are usually mild and often get better as your body gets used to it. Tell your doctor if they bother you or do not go away.
Stop using it and get medical help straight away if you notice:
- Thoughts of harming yourself or ending your life
- Feeling very high, overexcited or reckless (mania)
- Fever, sweating, shaking, muscle twitching, fast heartbeat and confusion (possible serotonin syndrome)
- A fit (seizure)
- Unusual bleeding or bruising, or black stools
- Confusion, headache and weakness, especially in older people (low sodium)
- A fast, pounding or uneven heartbeat, or fainting
- Being unable to pass urine
- Eye pain with blurred vision and red eye
This is not a complete list. If you notice anything unusual, ask your doctor or pharmacist.
- Take it with or after food to reduce stomach upset. Many people take it at bedtime.
- Most people start with 25 mg a day. Your doctor will raise it slowly, often to 100 mg to 150 mg, up to 250 mg a day.
- It can take 6 to 12 weeks to see the full effect on OCD.
If you miss a dose: Take it as soon as you remember, unless it is nearly time for your next dose. Never take two doses at once.
If you use too much: Contact your doctor, a poison control centre or your local emergency number straight away, even if you feel fine. Take the pack with you.
How to store it: Keep it in its original pack at room temperature (below 25°C / 77°F), away from heat, damp and direct sunlight. Do not use it after the expiry date.
- QHow long does Anafranil take to work?
- A
Some people notice better sleep or energy in 1 to 2 weeks, but it usually takes 4 to 6 weeks to feel the full benefit on mood. Keep taking it even if you do not feel different straight away.
- QHow long will I need to take Anafranil?
- A
Most people take it for at least 6 months after they feel better, to stop the depression or anxiety coming back. Your doctor will review this with you.
- QCan I drink alcohol with Anafranil?
- A
It is best to avoid alcohol. It can make you more drowsy and can make depression and anxiety worse.
- QIs Anafranil addictive?
- A
No, antidepressants are not addictive. But stopping suddenly can cause withdrawal-like symptoms, so always reduce slowly with your doctor.

Hamza Torres –
Here is my honest feedback on my order. Packaging was clean and professional. Happy with how my Clomipramine order turned out.
Viktor Jimenez –
I decided to try this site and it turned out well. The expiry date was fine and everything looked as it should. I reached out with a small query and it was sorted straight away. The whole ordering process felt easy and well organised. I would order Clomipramine here again.
Noah Cruz –
I have ordered from here before and it went well again. Creating an account and ordering was painless. And everything was in order when I opened the box. The cost was clearly shown before I paid, so no nasty surprises.
Riley Mehta –
Decided to order Anafranil here and it went smoothly. The outer box was discreet and the inside was well arranged. Five stars from me.
Aria Hussein –
Tried this site for the first time and had a good experience. Browsing the site was pleasant and the search worked well. Prices here are easy on the pocket.
Mia Volkov –
The team kept me updated on my order status. Highly satisfied with the service. The pages loaded fast and everything was easy to read.
Marco Coleman –
Ordered Clomipramine a few days ago and wanted to leave a quick review. I was happy with how carefully it was packed.
Ana Müller –
I was a little nervous about ordering Anafranil online, but it turned out fine. The seals were intact and everything looked fresh. I found the cost to be better than what I saw elsewhere. I am satisfied and will come back for my next order.
William Nowak –
I ordered from here after comparing a few options. The product matched the description on the page. Would not hesitate to use this site again.
Sameer Wagner –
My experience with this order was good. My Clomipramine reached me without any delays. It was packed with care, which I really noticed.
Abigail Marino –
Ordering from this site was easy. Good communication, I always knew what was happening with my order. No complaints about the product. Will be using this site again.
Luna Campbell –
My Anafranil order went through without a hitch. They answered my email within a day. I think the pricing is fair for what you get.
Fatima Saxena –
This was my second order from the site. Whenever I needed help, someone got back to me promptly. Everything inside was snug and protected. Good place to order Anafranil online.
Alexander Nasser –
Placing the order took only a few minutes. My Clomipramine matched the description on the page. No problems at all, so I am pleased.
Chinedu Morgan –
My Anafranil was packed with care, which I really noticed. No surprise fees at checkout, which I appreciated.
Isaac Petrov –
I used this site for my latest order and had no problems. Support was friendly and cleared up my doubt quickly. On top of that, the box was sturdy and the contents were well protected.