Desvenlafaxine (Pristiq)
$1.90
Pristiq contains Desvenlafaxine and treats depression by balancing brain chemicals to improve mood and energy.
Drug Information
7 reviews for Desvenlafaxine (Pristiq)
Pristiq contains Desvenlafaxine.
Desvenlafaxine is an antidepressant from a group called SNRIs. It is used to treat depression.
It is the active substance that venlafaxine turns into in the body, and it comes as a once-a-day extended-release tablet.
What is it used for?
- Depression in adults
How does it work?
Desvenlafaxine keeps more of two chemical messengers, serotonin and noradrenaline, available in the brain, which helps improve mood and energy.
This information is written in simple words to help you understand this product. It does not replace advice from your doctor or pharmacist.
Read these points before you start. If any of them apply to you, talk to your doctor or pharmacist first.
- Antidepressants can, rarely, cause thoughts of self-harm or suicide, especially in people under 25 and in the first few weeks. Tell someone close to you that you are taking it and ask them to tell you if they notice changes in your mood or behaviour.
- Do not take it with, or within 2 weeks of, an MAOI antidepressant (such as phenelzine or selegiline), or with linezolid or methylene blue.
- Taking it with other medicines that raise serotonin (other antidepressants, tramadol, triptans for migraine, lithium, St John's wort) can cause serotonin syndrome.
- It can raise the risk of bleeding, especially with aspirin, ibuprofen, naproxen or blood thinners.
- Tell your doctor if you have epilepsy, bipolar disorder or mania, glaucoma, heart problems, liver or kidney problems, or diabetes.
- Do not stop taking it suddenly. This can cause withdrawal symptoms like dizziness, electric-shock feelings, bad dreams and irritability. Your doctor will lower the dose slowly.
- It may make you sleepy or dizzy. Do not drive until you know how it affects you, and avoid alcohol.
- Tell your doctor if you are pregnant, planning a pregnancy or breastfeeding.
- It can raise blood pressure. Your doctor may check it regularly.
- Tell your doctor or pharmacist about every other medicine, vitamin or herbal product you use.
- Keep this product out of the reach and sight of children.
Like all medicines, Pristiq can cause side effects, but not everybody gets them.
Common side effects
- Feeling sick (nausea), especially in the first 1 to 2 weeks
- Headache
- Trouble sleeping or feeling sleepy
- Sweating
- Dry mouth
- Lower sex drive, or trouble reaching orgasm or getting an erection
- Constipation
- Dizziness
These are usually mild and often get better as your body gets used to it. Tell your doctor if they bother you or do not go away.
Stop using it and get medical help straight away if you notice:
- Thoughts of harming yourself or ending your life
- Feeling very high, overexcited or reckless (mania)
- Fever, sweating, shaking, muscle twitching, fast heartbeat and confusion (possible serotonin syndrome)
- A fit (seizure)
- Unusual bleeding or bruising, or black stools
- Confusion, headache and weakness, especially in older people (low sodium)
This is not a complete list. If you notice anything unusual, ask your doctor or pharmacist.
- Take it once a day, at the same time each day, with or without food.
- Swallow the tablet whole with water. Do not crush, chew or split it. You may see a tablet shell in your stool, which is normal.
- The usual adult dose is 50 mg once a day.
If you miss a dose: Take it as soon as you remember, unless it is nearly time for your next dose. Never take two doses at once.
If you use too much: Contact your doctor, a poison control centre or your local emergency number straight away, even if you feel fine. Take the pack with you.
How to store it: Keep it in its original pack at room temperature (below 25°C / 77°F), away from heat, damp and direct sunlight. Do not use it after the expiry date.
- QHow long does Pristiq take to work?
- A
Some people notice better sleep or energy in 1 to 2 weeks, but it usually takes 4 to 6 weeks to feel the full benefit on mood. Keep taking it even if you do not feel different straight away.
- QHow long will I need to take Pristiq?
- A
Most people take it for at least 6 months after they feel better, to stop the depression or anxiety coming back. Your doctor will review this with you.
- QCan I drink alcohol with Pristiq?
- A
It is best to avoid alcohol. It can make you more drowsy and can make depression and anxiety worse.
- QIs Pristiq addictive?
- A
No, antidepressants are not addictive. But stopping suddenly can cause withdrawal-like symptoms, so always reduce slowly with your doctor.

Yuki Mbeki –
A friend told me about this site, so I gave it a go. I found Desvenlafaxine on the site quickly and checkout was simple. I am glad I tried this site.
Kai Ivanov –
Just received my Desvenlafaxine and wanted to share how it went. Payment went through smoothly on the first try. Another good thing: the total I saw at checkout was the total I paid. It came well wrapped and in perfect condition. Happy with the experience overall.
Lin Gomez –
Picked up my Desvenlafaxine from this site and I am glad I did. No complaints about the product. Reasonably priced and the discount at checkout was a nice touch.
Ming Green –
My Desvenlafaxine order went through without a hitch. Pricing was reasonable and there were no hidden charges. And the packaging was neat and secure. The quantity was right and everything was accounted for. Nothing negative to say, it was a good one.
Tunde Menon –
My experience with this order was good. Adding Desvenlafaxine to the cart and paying was quick. I should add that shipping was fast for me.
Jacob Gupta –
My order went through without any problems. It was what I expected when I opened it. And the price was fair compared to other places I checked.
Fernando Liu –
I ordered from here after comparing a few options. Tracking worked well and the delivery went exactly as planned.