Bupropion (Wellbutrin SR)
$0.84
Wellbutrin SR is a slow release form of Bupropion used to treat depression and to help people stop smoking.
Drug Information
5 reviews for Bupropion (Wellbutrin SR)
Wellbutrin SR contains Bupropion.
Bupropion is an antidepressant that works differently from most others. It is used for depression and to help people stop smoking.
It is less likely than many antidepressants to cause weight gain or sexual side effects.
What is it used for?
- Depression
- Seasonal affective disorder (winter depression)
- Helping people stop smoking
How does it work?
Bupropion increases two brain chemicals, dopamine and noradrenaline, which help with mood, motivation and energy. It also reduces nicotine cravings and withdrawal symptoms.
This information is written in simple words to help you understand this product. It does not replace advice from your doctor or pharmacist.
Read these points before you start. If any of them apply to you, talk to your doctor or pharmacist first.
- Antidepressants can, rarely, cause thoughts of self-harm or suicide, especially in people under 25 and in the first few weeks. Tell someone close to you that you are taking it and ask them to tell you if they notice changes in your mood or behaviour.
- Do not take it with, or within 2 weeks of, an MAOI antidepressant (such as phenelzine or selegiline), or with linezolid or methylene blue.
- Taking it with other medicines that raise serotonin (other antidepressants, tramadol, triptans for migraine, lithium, St John's wort) can cause serotonin syndrome.
- It can raise the risk of bleeding, especially with aspirin, ibuprofen, naproxen or blood thinners.
- Tell your doctor if you have epilepsy, bipolar disorder or mania, glaucoma, heart problems, liver or kidney problems, or diabetes.
- Do not stop taking it suddenly. This can cause withdrawal symptoms like dizziness, electric-shock feelings, bad dreams and irritability. Your doctor will lower the dose slowly.
- It may make you sleepy or dizzy. Do not drive until you know how it affects you, and avoid alcohol.
- Tell your doctor if you are pregnant, planning a pregnancy or breastfeeding.
- Do not take it if you have epilepsy or have ever had a seizure, an eating disorder (anorexia or bulimia), or if you are suddenly stopping alcohol or sedatives. These raise the risk of seizures.
- Do not take it with other products that contain bupropion.
- It can raise blood pressure.
- Tell your doctor or pharmacist about every other medicine, vitamin or herbal product you use.
- Keep this product out of the reach and sight of children.
Like all medicines, Wellbutrin SR can cause side effects, but not everybody gets them.
Common side effects
- Trouble sleeping
- Dry mouth
- Headache
- Feeling sick
- Feeling anxious or shaky
These are usually mild and often get better as your body gets used to it. Tell your doctor if they bother you or do not go away.
Stop using it and get medical help straight away if you notice:
- Thoughts of harming yourself or ending your life
- Feeling very high, overexcited or reckless (mania)
- Fever, sweating, shaking, muscle twitching, fast heartbeat and confusion (possible serotonin syndrome)
- A fit (seizure)
- Unusual bleeding or bruising, or black stools
- Confusion, headache and weakness, especially in older people (low sodium)
This is not a complete list. If you notice anything unusual, ask your doctor or pharmacist.
- Take it in the morning. If you take it twice a day, leave at least 8 hours between doses and take the second dose no later than mid-afternoon.
- Swallow the tablet whole. Do not crush, chew or split it, as this can release too much at once and cause a seizure.
- For depression, a common dose is 150 mg once a day, up to 300 mg (SR: 150 mg twice a day; XL: 300 mg once a day).
- Never take more than prescribed, as the risk of seizures goes up with the dose.
If you miss a dose: Take it as soon as you remember, unless it is nearly time for your next dose. Never take two doses at once.
If you use too much: Contact your doctor, a poison control centre or your local emergency number straight away, even if you feel fine. Take the pack with you.
How to store it: Keep it in its original pack at room temperature (below 25°C / 77°F), away from heat, damp and direct sunlight. Do not use it after the expiry date.
- QHow long does Wellbutrin SR take to work?
- A
Some people notice better sleep or energy in 1 to 2 weeks, but it usually takes 4 to 6 weeks to feel the full benefit on mood. Keep taking it even if you do not feel different straight away.
- QHow long will I need to take Wellbutrin SR?
- A
Most people take it for at least 6 months after they feel better, to stop the depression or anxiety coming back. Your doctor will review this with you.
- QCan I drink alcohol with Wellbutrin SR?
- A
It is best to avoid alcohol. It can make you more drowsy and can make depression and anxiety worse.
- QIs Wellbutrin SR addictive?
- A
No, antidepressants are not addictive. But stopping suddenly can cause withdrawal-like symptoms, so always reduce slowly with your doctor.
- QDoes Wellbutrin SR cause weight gain?
- A
Usually not. Some people lose a little weight.

Nour Turner –
The Wellbutrin SR I got looked just like the listing. Everything was packed carefully and nothing was damaged.
Sebastian Malhotra –
Just got my order and everything went well. Good communication, I always knew what was happening with my order. The order form was short and easy to fill in. I could follow the shipment and it arrived as scheduled.
Luis Lim –
I tried this site for Bupropion after checking a couple of other places. It was cheaper than my usual place, and the service was just as good. The packing was discreet and tidy. I got a helpful reply when I asked about my order. Great experience, I have already bookmarked the site.
Alejandro Shah –
I appreciated the clear emails about my order. Would happily recommend it. It was wrapped well enough that I had no worry about damage.
Lei Long –
Delivery was quicker than I thought it would be. I should add that the customer team was respectful and answered everything I asked. Will come back to this site when I need Wellbutrin SR again.