Fluoxetine (Sarafem)
$0.54
Sarafem contains Fluoxetine and treats severe premenstrual symptoms (PMDD), easing mood swings, irritability and tension.
Drug Information
9 reviews for Fluoxetine (Sarafem)
Sarafem contains fluoxetine, an antidepressant from a group called SSRIs. In this form it is used to treat premenstrual dysphoric disorder (PMDD).
PMDD is a severe form of premenstrual syndrome. In the week or two before a period, it can cause strong mood swings, irritability, sadness, anxiety, tension and physical symptoms like bloating and breast tenderness.
What is it used for?
- Premenstrual dysphoric disorder (PMDD)
How does it work?
Fluoxetine helps keep more serotonin, a mood-controlling chemical messenger, available in the brain. In PMDD, it works quickly, often within the first cycle.
This information is written in simple words to help you understand this product. It does not replace advice from your doctor or pharmacist.
Read these points before you start. If any of them apply to you, talk to your doctor or pharmacist first.
- Antidepressants can, rarely, cause thoughts of self-harm or suicide, especially in people under 25 and in the first few weeks. Tell someone close to you that you are taking it and ask them to tell you if they notice changes in your mood or behaviour.
- Do not take it with, or within 2 weeks of, an MAOI antidepressant (such as phenelzine or selegiline), or with linezolid or methylene blue.
- Taking it with other medicines that raise serotonin (other antidepressants, tramadol, triptans for migraine, lithium, St John's wort) can cause serotonin syndrome.
- It can raise the risk of bleeding, especially with aspirin, ibuprofen, naproxen or blood thinners.
- Tell your doctor if you have epilepsy, bipolar disorder or mania, glaucoma, heart problems, liver or kidney problems, or diabetes.
- Do not stop taking it suddenly. This can cause withdrawal symptoms like dizziness, electric-shock feelings, bad dreams and irritability. Your doctor will lower the dose slowly.
- It may make you sleepy or dizzy. Do not drive until you know how it affects you, and avoid alcohol.
- Tell your doctor if you are pregnant, planning a pregnancy or breastfeeding.
- It can reduce the effect of tamoxifen.
- Tell your doctor or pharmacist about every other medicine, vitamin or herbal product you use.
- Keep this product out of the reach and sight of children.
Like all medicines, Sarafem can cause side effects, but not everybody gets them.
Common side effects
- Feeling sick (nausea), especially in the first 1 to 2 weeks
- Headache
- Trouble sleeping or feeling sleepy
- Sweating
- Dry mouth
- Lower sex drive, or trouble reaching orgasm or getting an erection
These are usually mild and often get better as your body gets used to it. Tell your doctor if they bother you or do not go away.
Stop using it and get medical help straight away if you notice:
- Thoughts of harming yourself or ending your life
- Feeling very high, overexcited or reckless (mania)
- Fever, sweating, shaking, muscle twitching, fast heartbeat and confusion (possible serotonin syndrome)
- A fit (seizure)
- Unusual bleeding or bruising, or black stools
- Confusion, headache and weakness, especially in older people (low sodium)
This is not a complete list. If you notice anything unusual, ask your doctor or pharmacist.
- Take it once a day, at the same time each day. Many people take it in the morning. If it makes you sleepy, take it in the evening.
- Swallow the tablet or capsule with water. You can take it with or without food. Taking it with food can help if it makes you feel sick.
- It can be taken every day, or only for the 14 days before your period is due. Your doctor will tell you which.
- The usual dose is 20 mg once a day.
If you miss a dose: Take it as soon as you remember, unless it is nearly time for your next dose. Never take two doses at once.
If you use too much: Contact your doctor, a poison control centre or your local emergency number straight away, even if you feel fine. Take the pack with you.
How to store it: Keep it in its original pack at room temperature (below 25°C / 77°F), away from heat, damp and direct sunlight. Do not use it after the expiry date.
- QHow long does Sarafem take to work?
- A
Some people notice better sleep or energy in 1 to 2 weeks, but it usually takes 4 to 6 weeks to feel the full benefit on mood. Keep taking it even if you do not feel different straight away.
- QHow long will I need to take Sarafem?
- A
Most people take it for at least 6 months after they feel better, to stop the depression or anxiety coming back. Your doctor will review this with you.
- QCan I drink alcohol with Sarafem?
- A
It is best to avoid alcohol. It can make you more drowsy and can make depression and anxiety worse.
- QIs Sarafem addictive?
- A
No, antidepressants are not addictive. But stopping suddenly can cause withdrawal-like symptoms, so always reduce slowly with your doctor.
- QDo I need to take Sarafem all month?
- A
Not always. Many women take it only for the 2 weeks before their period. Your doctor will advise you.

Aarav Park –
I have ordered Sarafem here before and this time was just as smooth. No complaints about the product. For the price, I could not ask for more. I would recommend this site to friends and family.
Lin Nair –
The customer team was respectful and answered everything I asked. I received everything in good time. Very satisfied with how it all went.
Asha Choi –
Picked up my Fluoxetine from this site and I am glad I did. Prices here are easy on the pocket. The wrapping was solid, nothing shifted around in transit. Nothing negative to say, it was a good one.
Daniel Rogers –
First time ordering here and it was a pleasant surprise. Good value for the money. I liked that the site did not make things complicated. It was what I expected when I opened it. Will be using this site again.
Chioma Nguyen –
Delivery was smooth with no surprises. A good experience from start to finish. The total I saw at checkout was the total I paid.
Caleb Mensah –
Wanted to share my experience with this order. Delivery was quicker than I thought it would be. The price was fair compared to other places I checked.
Thomas Gupta –
Tried this site for the first time and had a good experience. The parcel looked untouched when it got to me. The whole ordering process felt easy and well organised.
Amelie Saxena –
This was my second order from the site. The listing was easy to understand and nothing felt confusing. Honestly, the expiry date was fine and everything looked as it should.
Khalid Medina –
I placed an order last week and it was handled well. I got my order placed in no time. The team kept me updated on the status of my Fluoxetine order. I think the pricing is fair for what you get.