Cyproheptadine (Periactin)
$0.45
Periactin contains Cyproheptadine, an antihistamine for allergies and itching that is also sometimes used to stimulate appetite.
Drug Information
5 reviews for Cyproheptadine (Periactin)
Periactin contains Cyproheptadine.
Cyproheptadine is an antihistamine for allergies and itching. Doctors also sometimes use it to increase appetite and, in special cases, to treat serotonin syndrome.
What is it used for?
- Hay fever and other allergies
- Itching and hives
- Poor appetite (off-label)
How does it work?
Cyproheptadine blocks histamine and serotonin. Blocking histamine eases allergies. Blocking serotonin can increase appetite.
This information is written in simple words to help you understand this product. It does not replace advice from your doctor or pharmacist.
Read these points before you start. If any of them apply to you, talk to your doctor or pharmacist first.
- Tell your doctor if you have kidney or liver problems.
- Tell your doctor if you are pregnant or breastfeeding.
- Some people still feel a little sleepy. Do not drive until you know how it affects you, and be careful with alcohol.
- It can cause drowsiness. Do not drive, and avoid alcohol.
- Tell your doctor if you have glaucoma, an enlarged prostate, or asthma.
- Do not give it to children under 2 years.
- Tell your doctor or pharmacist about every other medicine, vitamin or herbal product you use.
- Keep this product out of the reach and sight of children.
Like all medicines, Periactin can cause side effects, but not everybody gets them.
Common side effects
- Drowsiness
- Increased appetite and weight gain
- Dry mouth
These are usually mild and often get better as your body gets used to it. Tell your doctor if they bother you or do not go away.
Stop using it and get medical help straight away if you notice:
- Signs of a serious allergic reaction, such as swelling of the face, lips or throat, or trouble breathing
- A fast or uneven heartbeat
This is not a complete list. If you notice anything unusual, ask your doctor or pharmacist.
- Take it 3 times a day, with or without food.
- A common adult dose is 4 mg three times a day. Do not take more than 32 mg a day.
- Swallow the tablet with water.
If you miss a dose: Take it as soon as you remember, unless it is nearly time for your next dose. Never take two doses at once.
If you use too much: Contact your doctor, a poison control centre or your local emergency number straight away, even if you feel fine. Take the pack with you.
How to store it: Keep it in its original pack at room temperature (below 25°C / 77°F), away from heat, damp and direct sunlight. Do not use it after the expiry date.
- QHow quickly does Periactin work?
- A
Most people feel relief within 1 to 3 hours.
- QCan I take Periactin every day?
- A
Yes. For hay fever or long-lasting hives, it can be taken every day during the season or for as long as needed.
- QCan I drink alcohol with Periactin?
- A
It is best to limit alcohol. Together they can make you more drowsy, even with antihistamines that do not usually cause sleepiness.

Chloe Fahmy –
I ordered from here after comparing a few options. The order form was short and easy to fill in. My Cyproheptadine came well wrapped and in perfect condition. I should add that shipping updates were clear, and the parcel turned up when promised. Pleased with the whole thing.
Mikhail Nasser –
Writing this after my latest order from the site. The seals were intact and everything looked fresh. No surprise fees at checkout, which I appreciated. Would happily recommend it.
Oluwaseun Osman –
I decided to try this site and it turned out well. The product matched the description on the page. On top of that, shipping was fast for me. I will be ordering Cyproheptadine from here again.
Elijah Gonzalez –
I was a bit unsure at first, but ordering here worked out fine. It was affordable and the total at checkout matched what I expected. It was dispatched fast and reached me soon after. Will come back to this site when I need Cyproheptadine again.
Ade Lin –
Everything was packed carefully and nothing was damaged. I think the pricing is fair for what you get. Got it faster than I was expecting, which was nice. A good experience from start to finish.