Lopinavir + Ritonavir (Kaletra)
$4.00
Kaletra combines Lopinavir and Ritonavir as part of HIV combination therapy to reduce the amount of virus in the body.
Drug Information
3 reviews for Lopinavir + Ritonavir (Kaletra)
Kaletra is an HIV medicine that contains two protease inhibitors, lopinavir and ritonavir, in one tablet. It is always used together with other HIV medicines.
What is it used for?
- HIV-1 infection in adults and children, as part of combination treatment
How does it work?
HIV needs an enzyme called protease to make new working virus particles. Lopinavir blocks this enzyme. Ritonavir slows down how fast the liver breaks down lopinavir, so it stays in the body longer and works better.
This information is written in simple words to help you understand this product. It does not replace advice from your doctor or pharmacist.
Read these points before you start. If any of them apply to you, talk to your doctor or pharmacist first.
- HIV medicines must be taken every day, exactly as prescribed. Missing doses can let the virus become resistant.
- These medicines do not cure HIV. With good treatment the amount of virus can become so low that it cannot be passed on through sex, but they do not protect against other infections.
- HIV medicines react with many other medicines, including some for cholesterol, heartburn, erection problems, TB, seizures and herbal remedies like St John's wort. Always check with your pharmacist first.
- Tell your doctor if you have liver problems (including hepatitis B or C), diabetes, haemophilia or heart problems.
- Tell your doctor if you are pregnant or planning a pregnancy.
- Tell your doctor if you have heart rhythm problems or pancreatitis.
- Tell your doctor or pharmacist about every other medicine, vitamin or herbal product you use.
- Keep this product out of the reach and sight of children.
Like all medicines, Kaletra can cause side effects, but not everybody gets them.
Common side effects
- Diarrhoea
- Feeling sick or being sick
- Headache or tiredness
- Higher cholesterol or blood sugar levels
These are usually mild and often get better as your body gets used to it. Tell your doctor if they bother you or do not go away.
Stop using it and get medical help straight away if you notice:
- Yellowing of the skin or eyes, or dark urine
- A severe rash, especially with fever, blisters or sore mouth
- Signs of a new infection or inflammation soon after starting treatment, as your immune system gets stronger
- Severe stomach pain spreading to your back (possible pancreatitis)
- Fainting or an uneven heartbeat
This is not a complete list. If you notice anything unusual, ask your doctor or pharmacist.
- Take it exactly as your doctor tells you, usually twice a day, or sometimes once a day.
- Swallow the tablets whole. Do not chew, break or crush them. You can take them with or without food.
- The usual adult dose is 400 mg lopinavir / 100 mg ritonavir twice a day.
- Take it with your other HIV medicines every day.
If you miss a dose: Take it as soon as you remember, unless it is nearly time for your next dose. Never take two doses at once. Try hard not to miss doses.
If you use too much: Contact your doctor, a poison control centre or your local emergency number straight away, even if you feel fine. Take the pack with you.
How to store it: Keep it in its original pack at room temperature (below 25°C / 77°F), away from heat, damp and direct sunlight. Do not use it after the expiry date.
- QWhy does Kaletra contain ritonavir?
- A
Ritonavir boosts lopinavir by stopping the liver breaking it down too quickly, so it stays at a strong level.
- QWhat can help with diarrhoea on Kaletra?
- A
Diarrhoea is common, especially at first. Drink plenty of fluids and ask your doctor about medicines that can help.
- QCan I take other medicines with Kaletra?
- A
Many medicines interact with it. Always check with your doctor or pharmacist before taking anything new, including herbal remedies.

Adaeze Coleman –
I was not left waiting long, the delivery was quick. The price was fair compared to other places I checked. Pleased with the whole thing.
Amelia Fahmy –
The team kept me updated on the status of my Kaletra order. I liked that the site did not make things complicated. Solid experience, nothing to complain about.
Musa Allen –
Good, careful packing with no dents or tears. I checked everything against my order and it was all correct. Would happily recommend it.